BWA

Open-source short-read aligner for mapping high-throughput sequencing reads to a reference genome.

Details

BWA is a widely used open-source short-read aligner that maps sequencing reads to a reference genome. It is commonly used in genome resequencing, variant calling, population genetics and sequencing data pre-processing.

Use cases: read alignment, reference genomes, variant calling, NGS data, bioinformatics

Note: usually combined with SAMtools, BCFtools, FastQC and MultiQC.